fig2
From: Oxidative stress-mediated inflammation promotes the pathogenesis of amyotrophic lateral sclerosis
Figure 2. ALS peripheral blood monocytes are pro-inflammatory. Expression of pro-inflammatory cytokine IL-1β gene as a marker of M1 macrophages in ALS monocytes is compared to normal control monocytes in the left panel. The expression of CD206 gene as a cell-surface protein marker of M2 is compared with normal control monocytes in the middle panel. The ratio of IL-1β/CD206 gene expressions is presented in the right panel. Monocytes of ALS patients (n = 43) were verified by qPCR and normalized to β-actin and normal control monocytes (n = 22). Error bars indicate the standard error, **P < 0.01 and **P < 0.05. ALS: Amyotrophic lateral sclerosis.
