fig1

Chronic intracerebroventricular administration is a reliable method in brain studies on monkeys

Figure 1. (A) The schedule of CSF sample collection. Cannula implantation was carried out in Week 11. ICV administration began in Week 1. CSF samples were collected in Weeks 12, 4, 9, 14, 19, 24, 29, 34, 39, 44, and 49. CSF sample collected at Week -12 was taken as the baseline. (B,C) Kruskal-Wallis H test revealed no significant difference between different time points in the average levels of CSF IL-1β (P = 0.597) and IL-6 (P = 0.112). Data are presented as mean ± standard deviation (SD). CSF: Cerebrospinal fluid; ICV: intracerebroventricular.

Ageing and Neurodegenerative Diseases
ISSN 2769-5301 (Online)

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